Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802722 | 0.89 | PARP1 (0.57) | GAATHRBGRIK1MEN1KMT2A | |
| SCHEMBL29200357 | 0.89 | PARP1 (0.57) | GAATHRBGRIK1MEN1KMT2A | |
| SCHEMBL29200359 | 0.86 | NTRK1 (0.55) | NTRK1NTRK2GAASAE1UBA2 | |
| SCHEMBL11051606 | 0.84 | MAOA (0.72) | GAAMAOAMAOBGRIK1MEN1 | |
| SCHEMBL19707566 | 0.83 | GAA (0.65) | GAAMAOAMAOBGRIK1MEN1 | |
| SCHEMBL29200426 | 0.83 | MEN1 (0.72) | MEN1KMT2ANPC1LMNAMAPT | |
| SCHEMBL30995906 | 0.83 | CNR1 (0.67) | GRIK1MEN1KMT2AGRIK2CNR1 | |
| SCHEMBL6521944 | 0.82 | TP53 (0.65) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL29556097 | 0.82 | MAOA (0.69) | GAAMAOAMAOBGRIK1MEN1 | |
| SCHEMBL29200375 | 0.82 | RAB9A (0.63) | GAASAE1UBA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |