Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200391 | 0.85 | MEN1 (0.66) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL11028218 | 0.84 | HTT (0.77) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL29200385 | 0.84 | TP53 (0.61) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL29200372 | 0.84 | MEN1 (0.78) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL29200423 | 0.84 | PTGER3 (0.60) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL29200404 | 0.84 | PTGER3 (0.60) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5153133 | 0.83 | TP53 (0.59) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL17976487 | 0.83 | TP53 (0.59) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL26082853 | 0.83 | MEN1 (0.62) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL6691064 | 0.82 | ALDH1A1 (0.50) | TP53KMT2ALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |