Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151876 | 0.89 | RAB9A (0.60) | TP53SMN1; SMN2BCAT2MEN1KMT2A | |
| SCHEMBL5632774 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AHTTLMNA | |
| SCHEMBL29200385 | 0.84 | TP53 (0.61) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL11028218 | 0.84 | HTT (0.77) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL5991743 | 0.83 | PTGS2 (0.63) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29200433 | 0.83 | SMN1; SMN2 (0.59) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL26082853 | 0.83 | MEN1 (0.62) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL17976487 | 0.83 | TP53 (0.59) | TP53EPHX1TSHREPHX2CDK9 | |
| SCHEMBL13329758 | 0.83 | ALDH1A1 (0.63) | SMN1; SMN2BCAT2POLBCXCL8NR1H4 | |
| SCHEMBL6431242 | 0.82 | MEN1 (0.68) | SMN1; SMN2MEN1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533967-B | Oil-in-water droplet type emulsion of active energy ray-curable resin composition and thermosensitive recording material | 日本化药株式会社 | 2023-09-15 | — | — | CN | disclosed |
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20030078249-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1235793-A2 | VLA-4 INTEGRIN ANTAGONISTS | Novartis AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| US-6432923-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | NOVARTIS AG (CH) | 2002-08-13 | — | — | US | disclosed |
| US-6407065-B1 | PREVENT CELL ADHESION; ANTIINFLAMMTORY AGENTS, RESPIRATORY SYSTEM DISORDERS | NOVARTIS AG (CH) | 2002-06-18 | — | — | US | disclosed |
| WO-2001042192-A2 | VLA-4 INTEGRIN ANTAGONISTS | NOVARTIS AG (CH) | 2001-06-14 | — | — | WO | disclosed |
| EP-1049665-A1 | VLA-4 ANTAGONISTS | Novartis AG (Novartis SA) (Novartis Inc.) (CH) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037605-A1 | VLA-4 ANTAGONISTS | NOVARTIS AG (CH) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078249-A1 | VLA-4 inhibitor compounds | VCAM1, ICAM1, ITGA4 | TP53 1309/4885EPHX1 1872/4885TSHR 3417/4885 |
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | TP53 1266/4885EPHX1 1645/4885TSHR 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.