Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11747092 | 0.98 | ALDH1A1 (0.49) | ALDH1A1HPGDL3MBTL1POLBKMT2A | |
| SCHEMBL10562641 | 0.84 | GAA (0.48) | ALDH1A1HPGDL3MBTL1POLBCYP1A2 | |
| SCHEMBL948318 | 0.83 | MAPT (0.59) | ALDH1A1HPGDL3MBTL1POLBKMT2A | |
| SCHEMBL4622869 | 0.83 | L3MBTL1 (0.56) | ALDH1A1HPGDL3MBTL1POLBKMT2A | |
| SCHEMBL7997788 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDPOLBHDAC3HDAC4 | |
| SCHEMBL8654405 | 0.83 | KCNK3 (0.57) | HPGDPOLBKMT2ATP53CYP1A2 | |
| SCHEMBL10896420 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDL3MBTL1POLBKMT2A | |
| SCHEMBL4172605 | 0.82 | L3MBTL1 (0.70) | ALDH1A1HPGDL3MBTL1POLBKMT2A | |
| SCHEMBL6475322 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDL3MBTL1POLBHTT | |
| SCHEMBL11747084 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDL3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | NORTHEASTERN UNIVERSITY | 2004-03-18 | — | — | US | claimed |
| WO-2002055512-A1 | XANTHENE DERIVATIVES | NORTHEASTERN UNIVERSITY (US) | 2002-07-18 | — | — | WO | claimed |
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-9527812-B2 | N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles | NORTHWESTERN UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | NORTHEASTERN UNIVERSITY | 2004-03-18 | — | — | US | disclosed |
| US-20040023806-A1 | N-phenylcarbamates having a microbicide insecticide and acaricide effect | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| WO-2002055512-A1 | XANTHENE DERIVATIVES | NORTHEASTERN UNIVERSITY (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023806-A1 | N-phenylcarbamates having a microbicide insecticide and acaricide effect | CBR3, CBR1, CYP1B1 | ALDH1A1 267/4885HPGD 3427/4885L3MBTL1 288/4885 |
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | IDO2, IDO1, TPH2 | ALDH1A1 1598/4885HPGD 647/4885L3MBTL1 3966/4885 |
| US-20040054195-A1 | Fluorescent dyes; photostability; labels, staining; analysis | ANXA5, XDH, TFEB | ALDH1A1 2790/4885HPGD 472/4885L3MBTL1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.