Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | STS | P08842 | 7/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192443 | 0.86 | ALDH1A1 (0.61) | KMT2AKDM4EMEN1 | |
| SCHEMBL441012 | 0.84 | KDM4E (0.62) | KMT2ASTSGPR119PTPN2PTPN1 | |
| SCHEMBL14655033 | 0.83 | MEN1 (0.63) | KMT2ASTSGPR119PTPN2PTPN1 | |
| SCHEMBL8343817 | 0.83 | KDM2B (0.51) | KMT2ASTSGPR119PTPN2PTPN1 | |
| SCHEMBL14655082 | 0.82 | KMT2A (0.54) | KMT2ASTSGPR119NPC1RAB9A | |
| SCHEMBL8346803 | 0.82 | KDM4E (0.55) | GPR119NPC1RAB9AKDM4EPKM | |
| SCHEMBL30848494 | 0.82 | KDM4E (0.55) | GPR119NPC1RAB9AKDM4EPKM | |
| SCHEMBL29200507 | 0.82 | TSHR (0.66) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5940516 | 0.81 | STS (0.57) | KMT2ASTSGPR119PTPN2PTPN1 | |
| SCHEMBL7838313 | 0.81 | GPR119 (0.62) | KMT2ASTSGPR119PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |