Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678793 | 0.94 | LMNA (0.76) | LMNAHPGDHTTTPSAB1CA1 | |
| SCHEMBL14761562 | 0.85 | LMNA (0.83) | LMNAHPGDHTTTPSAB1POLB | |
| SCHEMBL27892106 | 0.83 | LMNA (0.87) | LMNAHPGDHTTTPSAB1POLB | |
| SCHEMBL12674422 | 0.83 | LMNA (0.81) | LMNAHPGDHTTTPSAB1POLB | |
| SCHEMBL27892109 | 0.83 | HTT (0.81) | LMNAHPGDHTTTPSAB1POLB | |
| SCHEMBL14679461 | 0.83 | TPSAB1 (0.65) | LMNAHPGDTPSAB1CA1CA2 | |
| SCHEMBL14816841 | 0.83 | HPGD (1.00) | LMNAHPGDHTTPOLBALDH1A1 | |
| SCHEMBL4436696 | 0.83 | GAA (0.79) | LMNAHTTTPSAB1CA1CA2 | |
| SCHEMBL34461910 | 0.83 | HDAC3 (0.70) | LMNAHPGDTPSAB1CA1CA2 | |
| SCHEMBL1274285 | 0.82 | LMNA (0.68) | LMNAHPGDHTTTPSAB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |