Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437435 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GAATSHRHTTAPOBEC3A | |
| SCHEMBL19437440 | 0.84 | MEN1 (0.43) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL28508495 | 0.84 | PTGER4 (0.40) | ALDH1A1GAATSHRHTTAPOBEC3A | |
| SCHEMBL28515135 | 0.82 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL29200491 | 0.82 | LMNA (0.47) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL22135029 | 0.79 | STING1 (0.44) | GAAKMT2AMEN1 | |
| SCHEMBL19451673 | 0.79 | HTT (0.43) | ALDH1A1GAAKDM4ETSHRHTT | |
| SCHEMBL29868210 | 0.78 | TSHR (0.40) | ALDH1A1KDM4ETSHRHTTAPOBEC3A | |
| SCHEMBL19437488 | 0.77 | CYP2C9 (0.58) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL30469473 | 0.76 | TSHR (0.49) | ALDH1A1KDM4EMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |