Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783406 | 1.00 | MEN1 (0.54) | MEN1KMT2AATMMAPK14MAPT | |
| SCHEMBL12155648 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3199231 | 0.71 | MAPK1 (0.56) | MEN1KMT2AMAPK14MAPTALDH1A1 | |
| SCHEMBL30783416 | 0.71 | MEN1 (1.00) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL377486 | 0.71 | MEN1 (1.00) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL4376107 | 0.70 | MAPK14 (0.57) | MEN1KMT2AATMMAPK14MAPT | |
| SCHEMBL6584662 | 0.70 | KMT2A (0.54) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL6584068 | 0.70 | MEN1 (0.48) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL30783430 | 0.70 | KMT2A (0.70) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL29200844 | 0.70 | KMT2A (0.70) | MEN1KMT2AATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624043-A | Preparation method of quinolinone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |