Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075326 | 0.81 | CACNB4 (0.39) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL15712469 | 0.81 | ICMT (0.43) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL21295511 | 0.79 | PLA2G2A (0.48) | ALDH1A1MEN1KMT2AHPGDTDP1 | |
| SCHEMBL24824798 | 0.79 | CYP19A1 (0.44) | KDM4EMAPTALDH1A1MAPK1GAA | |
| SCHEMBL16727205 | 0.79 | PTGER4 (0.43) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL27112644 | 0.76 | LMNA (0.39) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL16729368 | 0.76 | PDE4A (0.46) | HTR6 | |
| SCHEMBL31035937 | 0.76 | PRKCI (0.46) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL930733 | 0.76 | PRKCI (0.46) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL11628385 | 0.75 | PTGER4 (0.50) | KDM4EMAPTALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332950-A | Indazole substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-06-27 | — | — | CN | claimed |
| CN-116332950-A | Indazole substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-06-27 | — | — | CN | disclosed |