Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990423 | 0.91 | MAPK1 (0.59) | OPRD1MAPK1LMNAHSD17B10TP53 | |
| SCHEMBL24447814 | 0.91 | MAPK1 (0.59) | OPRD1MAPK1LMNAHSD17B10TP53 | |
| SCHEMBL14395220 | 0.87 | MAPK1 (0.54) | OPRD1MAPK1LMNAHSD17B10TP53 | |
| SCHEMBL11990426 | 0.87 | MAPK1 (0.54) | OPRD1MAPK1LMNAHSD17B10TP53 | |
| SCHEMBL15481709 | 0.81 | OPRD1 (0.58) | OPRD1MEN1KMT2A | |
| SCHEMBL11969503 | 0.81 | OPRD1 (0.52) | OPRD1 | |
| SCHEMBL6852984 | 0.80 | SIGMAR1 (0.51) | OPRD1MAPK1 | |
| SCHEMBL19628590 | 0.80 | OPRD1 (0.56) | OPRD1MAPK1MEN1KMT2A | |
| SCHEMBL11990438 | 0.80 | OPRD1 (0.56) | OPRD1MAPK1MEN1KMT2A | |
| SCHEMBL18751633 | 0.80 | OPRD1 (0.56) | OPRD1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924153-A | Preparation method of key intermediate of donepezil bulk drug | 山东盛安贝新材料有限公司南京分公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924153-A | Preparation method of key intermediate of donepezil bulk drug | 山东盛安贝新材料有限公司南京分公司 | 2024-04-26 | — | — | CN | disclosed |