Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990438 | 1.00 | OPRD1 (0.56) | OPRD1MEN1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL19628590 | 1.00 | OPRD1 (0.56) | OPRD1MEN1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL11990424 | 0.91 | OPRD1 (0.54) | OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL4794878 | 0.90 | OPRD1 (0.53) | OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL6848584 | 0.89 | SIGMAR1 (0.50) | OPRD1SIGMAR1 | |
| SCHEMBL24447814 | 0.87 | MAPK1 (0.59) | OPRD1MEN1KMT2AMAPK1 | |
| SCHEMBL11990423 | 0.87 | MAPK1 (0.59) | OPRD1MEN1KMT2AMAPK1 | |
| SCHEMBL30150926 | 0.86 | SPHK2 (0.54) | OPRD1SIGMAR1 | |
| SCHEMBL11969174 | 0.86 | OPRD1 (0.51) | OPRD1MEN1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL5967865 | 0.86 | OPRD1 (0.51) | OPRD1MEN1KMT2ASLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981957-B2 | Synthetic process | THE UNIVERSITY OF LIVERPOOL (GB) | 2018-05-29 | — | — | US | disclosed |
| US-20170107208-A1 | SYNTHETIC PROCESS | THE UNIVERSITY OF LIVERPOOL (GB) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107208-A1 | SYNTHETIC PROCESS | PIR, SRM, SMS | OPRD1 264/4885MEN1 2575/4885KMT2A 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.