Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891909 | 1.00 | ITGB3 (0.46) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL31697753 | 0.83 | GPR119 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL4470355 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL29897978 | 0.82 | BRD4 (0.38) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL30014708 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL7452238 | 0.79 | ITGB3 (0.63) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27137550 | 0.79 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL21553790 | 0.78 | CHRM2 (0.44) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL28868759 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL27152049 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |