Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.58 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | F2R | P25116 | 6/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452238 | 0.93 | ITGB3 (0.63) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL30014708 | 0.93 | ITGB3 (0.68) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL26635197 | 0.89 | ITGB3 (0.50) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL30013612 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL27153790 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL27150060 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL22291286 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL30020028 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL28891909 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL29201726 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BGNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538111-B2 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2009-05-26 | — | — | US | disclosed |
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LTB4R2, BDKRB2, TBXA2R | ITGB3 4709/4885ITGA2B 4545/4885GNAO1 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.