Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334956 | 0.82 | DAO (0.50) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL24993293 | 0.77 | KDM4E (0.45) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL13994843 | 0.77 | ALOX15 (0.44) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL3057931 | 0.77 | PKM (0.37) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL10859551 | 0.75 | DAO (0.70) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL3055848 | 0.75 | DAO (0.39) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL5850753 | 0.74 | MAPT (0.68) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL31073398 | 0.73 | GSK3B (0.41) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL24993294 | 0.71 | KDM4E (0.42) | DAOMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL5919500 | 0.71 | MAPT (0.42) | DAOMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447443-A | Method for preparing rotirana intermediate by one-pot method | 北京康立生医药技术开发有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117447443-A | Method for preparing rotirana intermediate by one-pot method | 北京康立生医药技术开发有限公司 | 2024-01-26 | — | — | CN | disclosed |