SCHEMBL24993293

SCHEMBL24993293

CNC(=O)c1sc(C(C)=O)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
HPGD P15428 4/20 0.45
MAPT P10636 4/20 0.45
HTT P42858 2/20 0.45
HSD17B10 Q99714 1/20 0.45
ALDH1A1 P00352 6/20 0.38
NPSR1 Q6W5P4 2/20 0.38
DAO P14920 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
HDAC8 Q9BY41 3/20 0.36
HDAC6 Q9UBN7 3/20 0.36
HDAC2 Q92769 2/20 0.36
POLB P06746 1/20 0.36
PKM P14618 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16334956 0.79 DAO (0.50) KDM4EMAPTALDH1A1NPSR1DAO
SCHEMBL13994843 0.78 ALOX15 (0.44) KDM4EHPGDMAPTHTTHSD17B10
SCHEMBL29201822 0.77 DAO (0.41) KDM4EHPGDMAPTHTTALDH1A1
SCHEMBL12917962 0.76 ALDH1A1 (0.39) KDM4EHPGDMAPTHTTHSD17B10
SCHEMBL5850753 0.71 MAPT (0.68) KDM4EHPGDMAPTHTTHSD17B10
SCHEMBL19457471 0.71 LMNA (0.43) KDM4EHPGDHSD17B10ALDH1A1KMT2A
SCHEMBL5852668 0.71 KDM4E (0.61) KDM4EHPGDMAPTHTTHSD17B10
SCHEMBL29201807 0.70 GPR139 (0.32) KDM4EHPGDALDH1A1KMT2AHDAC6
SCHEMBL5919500 0.68 MAPT (0.42) KDM4EHPGDMAPTHTTHSD17B10
SCHEMBL24578032 0.68 MAPT (0.42) KDM4EHPGDMAPTHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012821-A1 A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) 2023-02-09 WO disclosed