Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184556 | 0.85 | KDM4E (0.46) | KDM4EAGTR1RAB9AGLAELANE | |
| Hydrochloric Acid SCHEMBL2955045 | 0.84 | KDM4E (0.45) | KDM4EAGTR1RAB9AGLAELANE | |
| SCHEMBL20274413 | 0.82 | KDM4E (0.50) | KDM4EAGTR1RAB9AGLAELANE | |
| SCHEMBL27611476 | 0.82 | KDM4E (0.44) | KDM4EAGTR1RAB9AGLAELANE | |
| SCHEMBL7959032 | 0.79 | ALDH1A1 (0.45) | KDM4ERAB9AELANEPRTN3ALDH1A1 | |
| SCHEMBL605325 | 0.79 | KDM4E (0.58) | KDM4ERAB9AELANEPRTN3ALDH1A1 | |
| SCHEMBL4761103 | 0.79 | TSHR (0.53) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL5180569 | 0.78 | GAA (0.48) | KDM4EAGTR1RAB9AGLAELANE | |
| SCHEMBL11416537 | 0.78 | CNR2 (0.55) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8584876 | 0.78 | KDM4E (0.56) | KDM4ERAB9AELANEPRTN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1371731-B1 | AMINOKETONE ASYMMETRIC REDUCTASE AND NUCLEIC ACID THEREOF | DAIICHI FINE CHEM CO LTD (JP) | 2010-09-08 | — | — | EP | claimed |