SCHEMBL605325

SCHEMBL605325

CCC(=O)c1ccccc1NC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.58
POLB P06746 1/20 0.58
ATM Q13315 1/20 0.58
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
ELANE P08246 1/20 0.45
PRTN3 P24158 1/20 0.45
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CLCN2 P51788 1/20 0.41
RECQL P46063 1/20 0.41
KCNA3 P22001 1/20 0.40
CRBN Q96SW2 1/20 0.40
GAA P10253 1/20 0.40
HSP90AB1 P08238 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8584876 0.98 KDM4E (0.56) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL7959032 0.84 ALDH1A1 (0.45) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL19131301 0.84 KDM4E (0.58) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL27611476 0.83 KDM4E (0.44) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL4184556 0.82 KDM4E (0.46) KDM4EPOLBALDH1A1SMN1; SMN2NPC1
SCHEMBL13623623 0.82 ALDH1A1 (0.64) KDM4EPOLBALDH1A1SMN1; SMN2NPC1
SCHEMBL12809405 0.82 KDM4E (0.56) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL9796404 0.82 KDM4E (0.56) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL11427052 0.82 KDM4E (0.56) KDM4EPOLBATMALDH1A1SMN1; SMN2
SCHEMBL22152375 0.82 KDM4E (0.43) KDM4EPOLBATMALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110050365-B Improved secondary lithium ion battery and lithium capacitor electrode compositions 汉高股份有限及两合公司 2023-04-28 CN claimed
CN-111186180-A High-film-separation VCM color-coated sheet for furniture 苏州兴禾源复合材料有限公司 2020-05-22 CN claimed
CN-108998779-B Chemical plating solution and environment-friendly alloy surface autocatalytic treatment method 绵阳高新区天力机械有限责任公司 2020-03-10 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-109772113-A A kind of deodorant of petrochemical industry sour gas 吕秀梅 2019-05-21 CN claimed
CN-109228597-A A kind of anti-rotten, pressure resistant type religion toy composite board 钱学华 2019-01-18 CN claimed
CN-108998779-A A kind of chemical plating fluid and environment-friendly type alloy surface self-catalysis processing method 四川鑫元瑞科技有限公司 2018-12-14 CN claimed
CN-108927868-A A kind of nontoxic non-stimulated religion toy timber preservative 钱学华 2018-12-04 CN claimed
CN-106378847-A Mould-proof and color fixing treatment agent for corn bran and using method of agent 安徽宏润工艺品有限公司 2017-02-08 CN claimed
CN-106349835-A Modified coating for architecture 李兆源 2017-01-25 CN claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
CN-1293039-C Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative SHANGHAI INST OF MEDICINE INDU (CN) 2007-01-03 CN claimed
CN-1610745-A Aminoketone asymmetric reductase and nucleic acid thereof DAIICHI FINE CHEM CO LTD (JP) 2005-04-27 CN claimed
CN-1583714-A Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative SHANGHAI MEDICAL INDUSTRY ACAD (CN) 2005-02-23 CN claimed
US-20040247583-A1 Aminoketone asymmetric reductase and nucleic acid thereof DAIICHI FINE CHEMICAL CO., LTD. (JP) 2004-12-09 US claimed
EP-1371731-A1 AMINOKETONE ASYMMETRIC REDUCTASE AND NUCLEIC ACID THEREOF Daiichi Fine Chemical Co., Ltd. (JP) 2003-12-17 EP claimed
EP-0461113-A1 TANNIN MANNICH ADDUCTS FOR IMPROVING CORROSION RESISTANCE OF METALS HENKEL CORPORATION (US) 1991-12-18 EP claimed
WO-1990005794-A1 TANNIN MANNICH ADDUCTS FOR IMPROVING CORROSION RESISTANCE OF METALS HENKEL CORPORATION (US) 1990-05-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040247583-A1 Aminoketone asymmetric reductase and nucleic acid thereof DHFR, MDH1, DPYD KDM4E 705/4885POLB 421/4885ATM 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.