Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605325 | 0.84 | KDM4E (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| SCHEMBL27611476 | 0.83 | KDM4E (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| SCHEMBL4184556 | 0.82 | KDM4E (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| SCHEMBL13623623 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL8584876 | 0.82 | KDM4E (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| Hydrochloric Acid SCHEMBL2955045 | 0.81 | KDM4E (0.45) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| SCHEMBL6421670 | 0.81 | CYP2C19 (0.61) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL30040195 | 0.81 | CYP2C19 (0.61) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7373425 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AELANE | |
| SCHEMBL13990159 | 0.80 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268512-B1 | HEATING PROPIONYLPHENYLHYDRAZIDE IN PRESENCE OF CALCIUM OXIDE IN SOLVENT TO PRODUCE 3-METHYL-2-OXOINDOLINE | MEDICAL INFORMATION SERVICES, INC. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1052251-A1 | PROCESS FOR THE PREPARATION OF 3-METHYL-2-OXOINDOLINE | Medical Information Services, Inc. (JP) | 2000-11-15 | — | — | EP | disclosed |
| CN-1253543-A | Process for producing ketoprofen and 5-benzoyl-3-methyl-2-indolinone | MEDICAL INFORMATION SERVICES I (JP) | 2000-05-17 | — | — | CN | disclosed |
| EP-0990637-A1 | PROCESS FOR PRODUCING KETOPROFEN AND 5-BENZOYL-3-METHYL-2-INDOLINONE | Medical Information Services, Inc. (JP) | 2000-04-05 | — | — | EP | disclosed |