Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892482 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL21114150 | 0.77 | CYP3A4 (0.57) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL2797723 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL22075510 | 0.71 | PGK1 (0.38) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL30211607 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL29202433 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL2180477 | 0.70 | CYP3A4 (0.67) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL6791668 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL1875968 | 0.69 | GABRP (0.41) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL2799266 | 0.69 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370130-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-117642170-A | Therapeutic compounds and methods | 基因泰克公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023287793-A1 | THERAPEUTIC COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2023-01-19 | — | — | WO | disclosed |