SCHEMBL292025

SCHEMBL292025

C/C=C\c1ccc(CC(=O)O)c(OC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.63
TYR P14679 2/20 0.55
ALDH1A1 P00352 6/20 0.52
MAPT P10636 7/20 0.51
KDM4E B2RXH2 4/20 0.51
HSD17B10 Q99714 4/20 0.49
HPGD P15428 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
ALOX15 P16050 2/20 0.49
MAPK1 P28482 2/20 0.49
LMNA P02545 4/20 0.48
HTT P42858 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
NFE2L2 Q16236 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3749071 1.00 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL31089445 1.00 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL292026 1.00 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
Acetic Acid SCHEMBL30853555 0.97 POLB (0.60) POLBTYRALDH1A1MAPTKDM4E
Cis/Trans-Isoeugenol SCHEMBL30541671 0.91 TYR (0.65) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL16859602 0.90 POLB (0.60) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL31352617 0.90 POLB (0.60) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL29062127 0.84 ALDH1A1 (0.56) POLBALDH1A1MAPTKDM4EHSD17B10
SCHEMBL25689618 0.82 TYR (0.59) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL4650941 0.79 POLB (0.53) POLBTYRALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
EP-2145042-B1 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2018-01-17 EP disclosed
US-8153848-B2 Homoallyl alcohols useful as fragrances GIVAUDAN SA (CH) 2012-04-10 US disclosed
EP-2220019-B1 HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES GIVAUDAN SA (CH) 2012-03-14 EP disclosed
US-20110130470-A1 Homoallyl Alcohols Useful as Fragrances GIVAUDAN SA (CH) 2011-06-02 US disclosed
EP-2220019-A1 HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES Givaudan SA (CH) 2010-08-25 EP disclosed
EP-2145042-A1 TEXTILE SCENTING Henkel AG & Co. KGaA (DE) 2010-01-20 EP disclosed
WO-2009065244-A1 HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES GIVAUDAN SA (CH) 2009-05-28 WO disclosed
WO-2008135306-A1 TEXTILE SCENTING HENKEL AG & CO. KGAA (DE) 2008-11-13 WO disclosed
EP-1928992-A1 CONSUMER PRODUCTS HAVING VARYING ODORS Henkel AG & Co. KGaA (DE) 2008-06-11 EP disclosed
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP disclosed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130470-A1 Homoallyl Alcohols Useful as Fragrances ADH5, HRH1, HRH3 POLB 3907/4885TYR 3011/4885ALDH1A1 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.