SCHEMBL4650941

SCHEMBL4650941

C/C=C/c1ccc(C[C@H](N)C(=O)O)c(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.53
GRIK1 P39086 1/20 0.52
GRIK2 Q13002 1/20 0.52
TYR P14679 1/20 0.49
ALDH1A1 P00352 6/20 0.47
MAPT P10636 6/20 0.46
KDM4E B2RXH2 4/20 0.46
LMNA P02545 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 3/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NFE2L2 Q16236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31181300 0.85 TRPA1 (0.48) POLBGRIK1GRIK2ALDH1A1MAPT
SCHEMBL31089445 0.79 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL3749071 0.79 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL5794029 0.79 KDM4E (0.55) POLBALDH1A1MAPTKDM4ELMNA
SCHEMBL292026 0.79 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL292025 0.79 POLB (0.63) POLBTYRALDH1A1MAPTKDM4E
SCHEMBL5794030 0.79 KDM4E (0.55) POLBALDH1A1MAPTKDM4ELMNA
SCHEMBL29519833 0.79 HSD17B10 (0.49) POLBALDH1A1MAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL8862614 0.78 HSD17B10 (0.48) ALOX15HSD17B10MEN1KMT2APKM
SCHEMBL13957330 0.77 LDHA (0.50) POLBALDH1A1MAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1962792-A1 COSMETIC AGENTS HAVING INCREASED FRAGRANCE INTENSITY AND PERSISTENCE Henkel AG & Co. KGaA (DE) 2008-09-03 EP disclosed
WO-2007068339-A1 COSMETIC AGENTS HAVING INCREASED FRAGRANCE INTENSITY AND PERSISTENCE HENKEL AG & CO. KGAA (DE) 2007-06-21 WO disclosed