Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204584 | 0.85 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL28432352 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL29204630 | 0.84 | OPRM1 (0.44) | SMN1; SMN2POLBTDP1OPRM1 | |
| SCHEMBL29204629 | 0.84 | CYP3A4 (0.44) | HTTALDH1A1MAPTLMNAS1PR4 | |
| SCHEMBL28388854 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL13041535 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2GAAHTTALDH1A1MEN1 | |
| SCHEMBL8342856 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1607897 | 0.69 | MEN1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL250872 | 0.68 | ALDH1A1 (0.52) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3022089 | 0.68 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658888-A | Sulfonylation five-membered lactam derivative and preparation method thereof | 安徽师范大学 | 2024-03-08 | — | — | CN | disclosed |