Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204673 | 0.85 | SMN1; SMN2 (0.36) | OPRM1 | |
| SCHEMBL29204629 | 0.85 | CYP3A4 (0.44) | OPRM1CNR2CNR1 | |
| SCHEMBL29204630 | 0.85 | OPRM1 (0.44) | OPRM1 | |
| SCHEMBL28388854 | 0.85 | ALDH1A1 (0.50) | OPRM1 | |
| SCHEMBL1607897 | 0.84 | MEN1 (0.42) | — | |
| SCHEMBL14174752 | 0.76 | OPRM1 (0.49) | OPRM1CNR2CNR1 | |
| SCHEMBL27406330 | 0.75 | ALDH1A1 (0.31) | CNR2HCRTR2 | |
| SCHEMBL4168719 | 0.75 | OPRM1 (0.48) | OPRM1CNR2 | |
| SCHEMBL30442545 | 0.72 | RAB9A (0.44) | OPRM1CNR2HCRTR2CNR1 | |
| SCHEMBL15215888 | 0.72 | RAB9A (0.44) | OPRM1CNR2HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658888-A | Sulfonylation five-membered lactam derivative and preparation method thereof | 安徽师范大学 | 2024-03-08 | — | — | CN | disclosed |