Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 4/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.51 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204835 | 0.94 | XPO1 (0.74) | XPO1TP53GAAMAPTALDH1A1 | |
| SCHEMBL29204841 | 0.90 | XPO1 (0.66) | XPO1TP53GAAMAPTALDH1A1 | |
| SCHEMBL29204805 | 0.90 | XPO1 (0.88) | XPO1TP53MAPTALDH1A1MEN1 | |
| SCHEMBL30883146 | 0.90 | XPO1 (0.88) | XPO1TP53MAPTALDH1A1MEN1 | |
| SCHEMBL29204840 | 0.89 | XPO1 (1.00) | XPO1TP53GAAMAPTALDH1A1 | |
| SCHEMBL30883142 | 0.88 | XPO1 (1.00) | XPO1TP53MAPTALDH1A1MEN1 | |
| SCHEMBL29204833 | 0.88 | XPO1 (1.00) | XPO1TP53MAPTALDH1A1MEN1 | |
| SCHEMBL29204824 | 0.84 | XPO1 (0.61) | XPO1TP53GAAMAPTSRPK1 | |
| SCHEMBL30883139 | 0.84 | XPO1 (0.77) | XPO1TP53MAPTALDH1A1MEN1 | |
| SCHEMBL29204831 | 0.84 | XPO1 (0.77) | XPO1TP53MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |