Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.52 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204815 | 0.90 | XPO1 (1.00) | XPO1GAATP53ALDH1A1SRPK1 | |
| SCHEMBL29204842 | 0.89 | XPO1 (0.80) | XPO1GAATP53ALDH1A1SRPK1 | |
| SCHEMBL29204835 | 0.83 | XPO1 (0.74) | XPO1GAATP53ALDH1A1SRPK1 | |
| SCHEMBL29204817 | 0.83 | XPO1 (0.80) | XPO1GAATP53ALDH1A1SRPK1 | |
| SCHEMBL29204830 | 0.79 | XPO1 (0.69) | XPO1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL30883143 | 0.79 | XPO1 (0.69) | XPO1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL29204841 | 0.79 | XPO1 (0.66) | XPO1GAATP53ALDH1A1KMT2A | |
| SCHEMBL29204804 | 0.78 | XPO1 (0.80) | XPO1GAATP53ALDH1A1SRPK1 | |
| SCHEMBL30883146 | 0.78 | XPO1 (0.88) | XPO1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL29204805 | 0.78 | XPO1 (0.88) | XPO1TP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |