Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828309 | 1.00 | HSD11B1 (0.41) | HSD11B1USP30ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29205132 | 0.88 | HSD11B1 (0.40) | HSD11B1MGLL | |
| SCHEMBL27166101 | 0.88 | HSD11B1 (0.44) | HSD11B1USP30ALDH1A1LMNAHSD17B10 | |
| SCHEMBL30055083 | 0.88 | HSD11B1 (0.44) | HSD11B1USP30ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27166031 | 0.85 | ALOX5 (0.48) | MEN1KMT2AALOX5MGLLPROKR1 | |
| SCHEMBL27166073 | 0.85 | ALOX5 (0.33) | HSD11B1ALOX5MGLLDPP4 | |
| SCHEMBL30055584 | 0.84 | MGLL (0.42) | HSD11B1USP30ALOX5MGLLKCNH2 | |
| SCHEMBL27166063 | 0.84 | MGLL (0.42) | HSD11B1USP30ALOX5MGLLKCNH2 | |
| SCHEMBL27166106 | 0.83 | HSD11B1 (0.41) | HSD11B1USP30MGLLPROKR1DPP4 | |
| SCHEMBL27166093 | 0.82 | HSD11B1 (0.38) | HSD11B1USP30ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |