Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206539 | 0.85 | ALDH1A1 (0.45) | ARLMNAALDH1A1RIPK1MAPK14 | |
| SCHEMBL30877820 | 0.85 | ALDH1A1 (0.45) | ARLMNAALDH1A1RIPK1MAPK14 | |
| SCHEMBL29206488 | 0.85 | AR (0.34) | AR | |
| SCHEMBL25436267 | 0.84 | ALDH1A1 (0.35) | ARLMNAALDH1A1HTTKDM4E | |
| SCHEMBL25423559 | 0.82 | GPR84 (0.41) | CYP1A2CYP2C19ALDH1A1MAPK14 | |
| SCHEMBL30483774 | 0.82 | GPR84 (0.41) | CYP1A2CYP2C19ALDH1A1MAPK14 | |
| SCHEMBL29206528 | 0.82 | CYP1A2 (0.39) | ARCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL29206562 | 0.81 | MEN1 (0.40) | CYP1A2CYP2C19LMNAALDH1A1MAPT | |
| SCHEMBL30053545 | 0.80 | MPO (0.44) | LMNAALDH1A1HTT | |
| SCHEMBL24243751 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |