Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30164912 | 1.00 | GPR119 (0.39) | GPR119ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL24824547 | 1.00 | GPR119 (0.39) | GPR119ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL24824546 | 0.77 | GPR119 (0.45) | GPR119ALDH1A1MAPTUSP2SMN1; SMN2 | |
| SCHEMBL12234858 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL9965941 | 0.75 | GPR119 (0.43) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL16187765 | 0.75 | GPR119 (0.43) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL10189711 | 0.75 | GPR119 (0.43) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL30164891 | 0.74 | PIK3CD (0.36) | GPR119ALDH1A1KMT2AMEN1 | |
| SCHEMBL29206642 | 0.74 | PIK3CD (0.36) | GPR119ALDH1A1KMT2AMEN1 | |
| SCHEMBL15024201 | 0.73 | GPR119 (0.53) | GPR119MAPTUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858872-A | Heterocyclic EGFR inhibitors for the treatment of cancer | 缆图药品公司 | 2024-04-09 | — | — | CN | disclosed |