Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24844739 | 0.85 | GAA (0.76) | GAALMNATDP1MAPTKMT2A | |
| SCHEMBL24844736 | 0.85 | GAA (0.76) | GAALMNATDP1MAPTKMT2A | |
| SCHEMBL24844742 | 0.83 | GAA (0.73) | GAALMNATDP1MAPTKMT2A | |
| SCHEMBL4115419 | 0.82 | PTGS2 (0.57) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1144017 | 0.80 | MAPT (0.64) | LMNATDP1MAPTKMT2ARXFP1 | |
| SCHEMBL29207098 | 0.80 | MAPT (0.64) | LMNATDP1MAPTKMT2ARXFP1 | |
| SCHEMBL8832017 | 0.78 | GAA (0.66) | GAALMNATDP1MAPTKMT2A | |
| SCHEMBL12061812 | 0.78 | GAA (0.66) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL27283394 | 0.78 | LMNA (0.66) | GAALMNATDP1MAPTKMT2A | |
| SCHEMBL28516840 | 0.76 | MAPT (0.56) | GAALMNAMAPTKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375641-A | C3-phenoxy substituted quinoline compound and synthetic method and application thereof | 杭州师范大学 | 2023-07-04 | — | — | CN | disclosed |