SCHEMBL29207397

SCHEMBL29207397

C=Cc1ccccc1O[PH](=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SRC P12931 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NFE2L2 Q16236 2/20 0.33
TFEB P19484 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
KDM4E B2RXH2 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
LMNA P02545 3/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
TLR2 O60603 1/20 0.31
ERN1 O75460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364661 0.82 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2SRC
SCHEMBL30716857 0.79 CA1 (0.35) ALDH1A1HPGDSMN1; SMN2SRCTSHR
SCHEMBL27748588 0.78 ALDH1A1 (0.35) ALDH1A1HPGDHTTSMN1; SMN2KMT2A
SCHEMBL27997955 0.77 ALDH1A1 (0.35) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL15048638 0.76 ALDH1A1 (0.47) ALDH1A1TSHRKDM4ELMNA
SCHEMBL9898071 0.74 NFE2L2 (0.41) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL3625298 0.73 ALDH1A1 (0.44) ALDH1A1HPGDHTTSMN1; SMN2SRC
SCHEMBL2791736 0.72 PTGDR2 (0.42) ALDH1A1HPGDHTTSMN1; SMN2SRC
SCHEMBL297297 0.72 ALDH1A1 (0.48) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL18037101 0.71 CA2 (0.48) ALDH1A1HPGDSMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113773345-B Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2024-05-03 CN claimed
CN-113773345-A Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2021-12-10 CN claimed
CN-113773345-B Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2024-05-03 CN disclosed
CN-113773345-B Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2024-05-03 CN disclosed
CN-113773345-A Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2021-12-10 CN disclosed
CN-113773345-A Method for preparing beta-carbonyl phosphonate compound 湖南科技学院 2021-12-10 CN disclosed