Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801285 | 0.86 | ALDH1A1 (0.49) | HRH4CYP11B2ALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL24671246 | 0.86 | PDE10A (0.40) | HRH4CYP11B2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL30066309 | 0.86 | PDE10A (0.40) | HRH4CYP11B2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL25200347 | 0.81 | GPR119 (0.40) | HRH4AOC3GRM5 | |
| SCHEMBL31306744 | 0.76 | PDE10A (0.40) | HRH4ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL29872807 | 0.75 | PRMT5 (0.41) | PDE10A | |
| SCHEMBL23459570 | 0.75 | PRMT5 (0.41) | PDE10A | |
| SCHEMBL31692696 | 0.75 | NT5E (0.40) | HRH4GRM5 | |
| SCHEMBL23984155 | 0.74 | PRMT5 (0.38) | HRH4CYP11B2ALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL25504062 | 0.74 | CNR2 (0.44) | HRH4CYP11B2ALDH1A1SMN1; SMN2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |