Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29208088 | 0.93 | SLC6A2 (0.46) | USP30MC4ROPRM1OPRL1GBA1 | |
| SCHEMBL29207994 | 0.85 | ALDH1A1 (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL29207980 | 0.81 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13543091 | 0.81 | ATM (0.49) | USP30RAB9AJAK3MEN1KMT2A | |
| SCHEMBL13543090 | 0.80 | USP30 (0.73) | USP30GBA1NPC1RAB9AALDH1A1 | |
| SCHEMBL29208108 | 0.77 | HTR2A (0.40) | USP30ALDH1A1SMN1; SMN2 | |
| SCHEMBL9546681 | 0.76 | ITGB3 (0.57) | USP30GBA1ALDH1A1HPGDNMT1 | |
| SCHEMBL30731030 | 0.76 | USP30 (0.51) | USP30OPRM1GBA1 | |
| SCHEMBL5265103 | 0.76 | RAB9A (0.73) | MC4RGBA1NPC1RAB9AJAK3 | |
| Hydrochloric Acid SCHEMBL1532746 | 0.75 | RAB9A (0.71) | MC4RGBA1NPC1RAB9AJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024067304-A1 | COMPOUND WITH INHIBITORY ACTIVITY AGAINST SIGMA2 AND 5HT2A AND USE | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |