Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608106 | 0.98 | CA2 (0.36) | CA2CA1AKR1B1MAPK1PAM | |
| SCHEMBL608718 | 0.91 | CES2 (0.39) | AKR1B1PPARGPPARDPPARATSHR | |
| SCHEMBL5690491 | 0.89 | CES2 (0.42) | PPARGPPARDPPARATSHRGPR84 | |
| Ammonia Solution, Strong SCHEMBL29022925 | 0.84 | AKR1B1 (0.36) | AKR1B1PAMPPARGPPARDPPARA | |
| SCHEMBL609525 | 0.84 | LMNA (0.39) | CA2CA1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL8646937 | 0.82 | CA1 (0.38) | CA2CA1PAMTSHRALDH1A1 | |
| SCHEMBL2702976 | 0.82 | AKR1B1 (0.37) | AKR1B1PAMPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL11627695 | 0.82 | LMNA (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL608105 | 0.82 | CA1 (0.38) | CA2CA1PAMALDH1A1HSD17B10 | |
| SCHEMBL31094245 | 0.81 | LMNA (0.30) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986205-A | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117986205-B | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-117986205-A | Isosteviol derivative and preparation method and application thereof | 广东工业大学 | 2024-05-07 | — | — | CN | disclosed |