Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900461 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1GAAPKMCHEK1 | |
| SCHEMBL30086903 | 0.71 | NNMT (0.41) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL11559241 | 0.70 | NOTUM (0.52) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL23888705 | 0.69 | HTT (0.44) | KDM4EALDH1A1GAAPKMCHEK1 | |
| SCHEMBL7233738 | 0.68 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAPKMCHEK1 | |
| SCHEMBL23147426 | 0.67 | NOTUM (0.52) | KDM4EALDH1A1GAAPKMTDP1 | |
| SCHEMBL23888694 | 0.67 | CHEK1 (0.40) | KDM4EALDH1A1GAAPKMCHEK1 | |
| SCHEMBL7996974 | 0.66 | KMT2A (0.38) | KDM4EALDH1A1GAAPKMDYRK1A | |
| SCHEMBL28147239 | 0.65 | MEN1 (0.53) | KDM4EALDH1A1CLK4KMT2AHPGD | |
| SCHEMBL6556406 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1GAAPKMCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777103-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720520-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| EP-4126844-A1 | AMIDE COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-02-08 | — | — | EP | disclosed |
| CN-115315422-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2022-11-08 | — | — | CN | disclosed |