Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426443 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208497 | 0.86 | SUCNR1 (0.35) | EPHX2BCHECNR2P2RY14SUCNR1 | |
| SCHEMBL29208477 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208377 | 0.81 | CCNC (0.40) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL25423743 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL24414605 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208414 | 0.75 | CCNC (0.38) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL25424830 | 0.74 | ALDH1A1 (0.49) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208475 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208415 | 0.74 | CCNC (0.36) | KDM4EALDH1A1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116391129-A | Target binding assays for RAS proteins | 普罗美加公司 | 2023-07-04 | — | — | CN | disclosed |
| US-20220064696-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | PROMEGA CORPORATION (US) | 2022-03-03 | — | — | US | disclosed |
| WO-2022047186-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | PROMEGA CORPORATION (US) | 2022-03-03 | — | — | WO | disclosed |