Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424948 | 0.90 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208368 | 0.89 | CCNC (0.42) | CCNCCDK8KDM4EALDH1A1TSHR | |
| SCHEMBL29208443 | 0.88 | CA1 (0.37) | PLK1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL29208420 | 0.88 | ALDH1A1 (0.37) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208414 | 0.86 | CCNC (0.38) | CCNCCDK8KDM4EALDH1A1TSHR | |
| SCHEMBL25424064 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29208377 | 0.79 | CCNC (0.40) | CCNCCDK8KDM4EALDH1A1TSHR | |
| SCHEMBL25423499 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL25426273 | 0.77 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL25424956 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116391129-A | Target binding assays for RAS proteins | 普罗美加公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022047186-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | PROMEGA CORPORATION (US) | 2022-03-03 | — | — | WO | disclosed |
| US-20220064696-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | PROMEGA CORPORATION (US) | 2022-03-03 | — | — | US | disclosed |