Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208382 | 0.85 | EP300 (0.43) | EP300HDAC1HDAC8HDAC2HDAC6 | |
| SCHEMBL29208378 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL25423945 | 0.82 | ALDH1A1 (0.46) | EP300ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL29208421 | 0.79 | ALDH1A1 (0.41) | EP300ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL29208411 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208420 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208441 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL25425260 | 0.68 | EP300 (0.45) | EP300HDAC1HDAC8HDAC2HDAC6 | |
| SCHEMBL29208495 | 0.68 | ADA (0.35) | HDAC1MCL1HDAC8HDAC2HDAC6 | |
| SCHEMBL1520652 | 0.68 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116391129-A | Target binding assays for RAS proteins | 普罗美加公司 | 2023-07-04 | — | — | CN | disclosed |