Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208411 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208388 | 0.83 | HDAC8 (0.42) | KDM4EAPPSNCABACE1PLAU | |
| SCHEMBL25426301 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL14783862 | 0.77 | FFAR1 (0.53) | GLAADRA1D | |
| SCHEMBL29208381 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29587490 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL1520652 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL29208366 | 0.73 | HDAC8 (0.47) | APPSNCABACE1PLAUPLG | |
| SCHEMBL30991821 | 0.73 | MAOB (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL24414699 | 0.73 | MAOB (0.56) | ALDH1A1KDM4ETSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116391129-A | Target binding assays for RAS proteins | 普罗美加公司 | 2023-07-04 | — | — | CN | disclosed |