Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 17/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208505 | 0.87 | EP300 (0.42) | EP300HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL25423945 | 0.84 | ALDH1A1 (0.46) | EP300HDAC1 | |
| SCHEMBL25426067 | 0.83 | CPB2 (0.36) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29208382 | 0.83 | EP300 (0.43) | EP300HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL25425543 | 0.73 | TSHR (0.49) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29208421 | 0.72 | ALDH1A1 (0.41) | EP300 | |
| SCHEMBL29208507 | 0.70 | NAMPT (0.37) | HDAC8 | |
| SCHEMBL25421576 | 0.70 | TSHR (0.51) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29208433 | 0.68 | EP300 (0.41) | EP300HDAC8HDAC1HDAC2HDAC6 | |
| SCHEMBL30991815 | 0.68 | MTNR1A (0.42) | HDAC8HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204808-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | Promega Corporation (US) | 2023-07-05 | — | — | EP | disclosed |