Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336438 | 1.00 | LMNA (0.46) | LMNANOTUMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5270784 | 0.84 | NOTUM (0.63) | LMNANOTUMMAPTTHRBMEN1 | |
| SCHEMBL29209024 | 0.83 | LMNA (0.51) | LMNANOTUMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30336534 | 0.83 | LMNA (0.51) | LMNANOTUMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5276056 | 0.83 | USP30 (0.50) | LMNANOTUMPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16042116 | 0.82 | NOTUM (0.43) | NOTUMUSP30MAPTPOLBDGAT1 | |
| SCHEMBL13524326 | 0.80 | NOTUM (0.69) | LMNANOTUMSLC22A12MAPTPOLB | |
| SCHEMBL4824285 | 0.76 | NAAA (0.49) | LMNANOTUMMAPTHTTRAB9A | |
| SCHEMBL31472162 | 0.76 | TP53 (0.44) | LMNANOTUMMAPTHTTRAB9A | |
| SCHEMBL304544 | 0.75 | PDK1 (0.43) | LMNANOTUMPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |