Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18007672 | 0.85 | TAAR1 (0.42) | TAAR1CYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL14661332 | 0.79 | NOS1 (0.42) | TAAR1CYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL21586420 | 0.76 | PDE10A (0.38) | TAAR1TSHRPDE10A | |
| SCHEMBL25773828 | 0.76 | KDM4E (0.37) | CYP3A4TP53ALDH1A1TSHRTDP1 | |
| SCHEMBL3825761 | 0.76 | NOS1 (0.45) | TAAR1CYP3A4TP53NOS1NOS2 | |
| SCHEMBL30487328 | 0.76 | KDM4E (0.37) | CYP3A4TP53ALDH1A1TSHRTDP1 | |
| SCHEMBL29209673 | 0.76 | OPRL1 (0.36) | CYP3A4TP53ALDH1A1TSHRTDP1 | |
| SCHEMBL21784221 | 0.75 | TDO2 (0.41) | TAAR1NOS1NOS2NOS3 | |
| SCHEMBL203946 | 0.75 | CYP3A4 (0.58) | CYP3A4TP53ALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL4006326 | 0.73 | CYP3A4 (0.55) | CYP3A4TP53ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |