Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26181289 | 0.79 | NOS3 (0.32) | NOS3NOS1NOS2KDM1AKDM1B | |
| SCHEMBL29526074 | 0.79 | NOS3 (0.32) | NOS3NOS1NOS2KDM1AKDM1B | |
| SCHEMBL30006278 | 0.76 | GAA (0.34) | NOS3NOS1NOS2KDM1AKDM1B | |
| SCHEMBL25773828 | 0.76 | KDM4E (0.37) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL30487328 | 0.76 | KDM4E (0.37) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL29209727 | 0.76 | TAAR1 (0.37) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL20681213 | 0.76 | GAA (0.34) | NOS3NOS1NOS2KDM1AKDM1B | |
| SCHEMBL20681119 | 0.76 | NLRP3 (0.30) | — | |
| SCHEMBL2032766 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL20681153 | 0.73 | HTR2C (0.39) | OPRL1CYP3A4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |