Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907263 | 0.89 | CA12 (0.55) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL12642017 | 0.83 | ALDH1A1 (0.50) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL30831293 | 0.82 | TSHR (0.56) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL28667122 | 0.82 | CA12 (0.46) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL17965928 | 0.79 | LMNA (0.50) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL17401074 | 0.78 | TDP1 (0.47) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL17965927 | 0.78 | RECQL (0.50) | HSD11B1RECQLALDH1A1TDP1TP53 | |
| SCHEMBL21151897 | 0.78 | ALDH1A1 (0.45) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL13333146 | 0.78 | MAPT (0.50) | HSD11B1RECQLALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL17688654 | 0.78 | ALDH1A1 (0.48) | CA12CA1CA2CA9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801107-A | Benzazepine derivatives, conjugates containing same and application thereof | 上海迪诺医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |