Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741377 | 0.74 | MAPT (0.58) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL29212287 | 0.73 | MAOA (0.36) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL31592520 | 0.72 | CA12 (0.53) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL11078522 | 0.72 | MAPT (0.53) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL28186756 | 0.72 | PYCR1 (0.53) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL566097 | 0.72 | MAPT (0.53) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL4225554 | 0.72 | CA12 (0.53) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL17076659 | 0.72 | CA12 (0.58) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL20540341 | 0.71 | MAPT (0.52) | CA12CA9MAPTCA2CA1 | |
| SCHEMBL25033085 | 0.71 | CA12 (0.51) | CA12CA9MAPTCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |