Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25966307 | 0.78 | CYP11B1 (0.33) | CYP11B2CYP3A4CYP11B1 | |
| SCHEMBL6629927 | 0.77 | ALDH1A1 (0.39) | ERN1CYP3A4ALDH1A1TSHR | |
| SCHEMBL31489084 | 0.76 | ERN1 (0.37) | ERN1 | |
| SCHEMBL112640 | 0.76 | LMNA (0.37) | ERN1ALDH1A1TSHR | |
| SCHEMBL6874690 | 0.75 | — | — | |
| SCHEMBL6118780 | 0.74 | ERN1 (0.36) | ERN1 | |
| SCHEMBL31378876 | 0.74 | ERN1 (0.36) | ERN1 | |
| SCHEMBL9142540 | 0.74 | CYP1A2 (0.35) | ERN1CYP3A4ALDH1A1TSHRDAO | |
| SCHEMBL23143277 | 0.74 | CA1 (0.38) | ERN1ALDH1A1TSHR | |
| SCHEMBL14822643 | 0.74 | CYP11B2 (0.35) | ERN1CYP11B2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026996-A | Preparation method of 1-cyclopropyl-5, 6-difluoro-2- (5-fluoro-4-methylpyridine-3-yl) -1H-benzo [ d ] imidazole | 无锡捷化医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |