Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213392 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BCTSLAKR1C4AKR1C3 | |
| SCHEMBL29213401 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BCTSLAKR1C4AKR1C3 | |
| SCHEMBL29213294 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BCTSLAKR1C4AKR1C3 | |
| SCHEMBL29213492 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL29213449 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL29213259 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL29213261 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL29213263 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3AKR1C2L3MBTL1 | |
| SCHEMBL30219112 | 0.84 | CTSL (0.50) | CTSLGRNSORT1 | |
| SCHEMBL30219101 | 0.84 | CTSL (0.50) | CTSLGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | disclosed |