Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213259 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BCASRL3MBTL1GRN | |
| SCHEMBL29213261 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BCASRL3MBTL1GRN | |
| SCHEMBL29213449 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BCASRL3MBTL1GRN | |
| SCHEMBL29213492 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BCASRL3MBTL1GRN | |
| SCHEMBL29213401 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BL3MBTL1GRNSORT1 | |
| SCHEMBL29213392 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BL3MBTL1GRNSORT1 | |
| SCHEMBL29213265 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BL3MBTL1GRNSORT1 | |
| SCHEMBL29213294 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BL3MBTL1GRNSORT1 | |
| SCHEMBL30219068 | 0.84 | RIPK1 (0.46) | GRNSORT1CYP2C9 | |
| SCHEMBL30219104 | 0.84 | RIPK1 (0.46) | GRNSORT1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | disclosed |