Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 4/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213382 | 1.00 | GRN (0.42) | GRNSORT1RIPK1VNN1PYGL | |
| SCHEMBL29213385 | 1.00 | GRN (0.42) | GRNSORT1RIPK1VNN1PYGL | |
| SCHEMBL29213384 | 1.00 | GRN (0.42) | GRNSORT1RIPK1VNN1PYGL | |
| SCHEMBL30219083 | 0.85 | NPSR1 (0.37) | GRNSORT1VNN1CYP2C9 | |
| SCHEMBL30219105 | 0.81 | RIPK1 (0.51) | GRNSORT1RIPK1CTSK | |
| SCHEMBL31052820 | 0.81 | GRN (0.45) | GRNSORT1RIPK1PYGLCYP2C9 | |
| SCHEMBL30219049 | 0.81 | RIPK1 (0.51) | GRNSORT1RIPK1CTSK | |
| Hydrochloric Acid SCHEMBL30219092 | 0.80 | RIPK1 (0.50) | GRNSORT1RIPK1CTSK | |
| SCHEMBL31052905 | 0.77 | GRN (0.41) | GRNSORT1PYGLCYP2C9ITGAV | |
| SCHEMBL29213329 | 0.76 | GRN (0.43) | GRNSORT1RIPK1VNN1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | disclosed |