Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276345 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP2A6RAB9A | |
| SCHEMBL27912021 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1TDP1CYP2A6 | |
| SCHEMBL2041747 | 0.76 | MEN1 (0.35) | MEN1KMT2AALDH1A1TDP1CYP2A6 | |
| SCHEMBL404196 | 0.76 | AHR (0.68) | MEN1KMT2ACYP2A6AHRNR1H2 | |
| SCHEMBL29422942 | 0.76 | AHR (0.68) | MEN1KMT2ACYP2A6AHRNR1H2 | |
| SCHEMBL28009932 | 0.76 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1CYP2A6 | |
| SCHEMBL10596187 | 0.74 | AHR (0.65) | MEN1KMT2ACYP2A6AHRNR1H2 | |
| Methane SCHEMBL27372843 | 0.74 | AHR (0.65) | MEN1KMT2ACYP2A6AHRNR1H2 | |
| Water SCHEMBL11700413 | 0.74 | AHR (0.65) | MEN1KMT2ACYP2A6AHRNR1H2 | |
| SCHEMBL4600429 | 0.74 | MEN1 (0.36) | MEN1KMT2AALDH1A1TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820303-A | Tetrahydroacridine-9 carboxylic acid derivative and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |