Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973832 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4EL3MBTL1PDE4BPDE4A | |
| SCHEMBL29213635 | 0.80 | MEN1 (0.42) | ALDH1A1CYP2A6ACLYBACE1MEN1 | |
| SCHEMBL6535860 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1PDE4BPDE4A | |
| SCHEMBL27812283 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1PDE4BPDE4A | |
| SCHEMBL11051285 | 0.77 | MEN1 (0.43) | ALDH1A1KDM4EL3MBTL1PDE4BPDE4A | |
| SCHEMBL17085611 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1PDE4BPDE4A | |
| SCHEMBL881433 | 0.74 | ERN1 (0.40) | ALDH1A1KDM4EERN1MAPT | |
| SCHEMBL6535962 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EPDE4BPDE4APDE4C | |
| SCHEMBL29672073 | 0.72 | ERN1 (0.45) | ALDH1A1KDM4EERN1LCKGLA | |
| SCHEMBL6535983 | 0.72 | ERN1 (0.45) | ALDH1A1KDM4EERN1LCKGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131655-A2 | TRI-ARYL/HETEROAROMATIC CANNABINOIDS AND USE THEREOF | The University of Tennessee Research Foundation (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008109027-A2 | TRI-ARYL/HETEROAROAROMATIC CANNABINOIDS AND USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2008-09-12 | — | — | WO | disclosed |